Nanoparticles Targeting the Infarcted Heart

http://pubs.acs.org/doi/abs/10.1021/nl2025882

 

A group at Massachusetts Institute of Technology, USA, reported a nanoparticulate system capable of targeting the heart after myocardial infarction (MI). Targeting is based on overexpression of angiotensin II type 1 (AT1) receptor in the infarcted heart. Liposomes 142 nm in diameter were conjugated with a ligand specific to AT1. The nanoparticles were able to specifically target cardiac cells in vitro, and in the infarcted heart after intravenous injection in vivo. This system may be useful for delivering therapeutic agents specifically to the infarcted heart.

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Hello world!

The term Nano is occupying a remarkable place in modern technology. But, I believe many of us are wondering what Nano can really do for us. The aim of this blog is to give an overview about the nanotechnology to students, academic heads aiming to start nanotechnology course in their institutes, and industrialists willing to know the potentiality of nanotechnology to influence their industry.

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